Tired, dull or slow-to-heal skin sometimes needs more than surface hydration – it needs support at a cellular repair level. PDRN Therapy uses polydeoxyribonucleotide, a naturally derived regenerative compound, to support tissue repair and skin revitalisation from within, offering a distinctive anti-inflammatory and healing-focused approach to skin rejuvenation.
At our Anna Nagar clinic, every PDRN Therapy session is performed only after a detailed skin assessment by experienced dermatologists to confirm suitability and determine the right treatment plan for your skin’s specific needs.
PDRN stands for polydeoxyribonucleotide, a compound made up of purified DNA fragments, most commonly derived from salmon, that has been used in regenerative medicine for tissue repair for several decades before becoming popular in aesthetic skin treatments. When injected into the skin, PDRN fragments bind to adenosine A2A receptors on cell surfaces, triggering a biological cascade that reduces inflammation while also supporting the formation of new blood vessels, a process known as angiogenesis.
This mechanism is what sets PDRN Therapy apart from other regenerative treatments: rather than working primarily through growth-factor signalling like PRP, or through mechanical injury like microneedling, PDRN works through this specific receptor-binding pathway that simultaneously calms inflammation and supports tissue repair and improved blood supply to the treated area. Improved microcirculation, in turn, helps deliver more oxygen and nutrients to skin cells, supporting overall tissue health and gradual revitalisation.
Because PDRN has a long-established safety record in regenerative and wound-healing medicine before its aesthetic use, it is often chosen by those wanting a treatment with this more established therapeutic background, alongside its skin-refining benefits. Results tend to build gradually across a course of sessions as the tissue-repair and anti-inflammatory effects accumulate, rather than delivering a dramatic single-session change.
At our Anna Nagar clinic, every PDRN Therapy session is performed only after a detailed skin assessment by experienced dermatologists to confirm suitability and determine the right treatment plan and injection technique for your skin’s specific needs.
PDRN Micro-Injection Therapy
30-45 Minutes
Men & Women
3-4 Recommended
Minimal
Required
₹5,500* Per Session
Final cost depends on the treatment area and number of sessions recommended during consultation.
PDRN Therapy has an established safety record in regenerative medicine.
"I had been struggling with hair thinning for over a year. After completing my PRP sessions at Anucare, I noticed significantly less hair fall within two months, and my hair feels much fuller now. The doctors explained every step clearly, and the entire experience was comfortable."

"The consultation was detailed, and the treatment plan was tailored to my condition. After four PRP sessions, I noticed visible improvement in my hair density and reduced hair fall. The doctors were professional, the staff was friendly, and every visit was comfortable. I'm happy with the results."

"I was initially unsure whether PRP would work for me, but the results exceeded my expectations. My hair has become noticeably thicker, and my confidence has improved. I highly recommend Anucare for anyone looking for effective hair restoration treatments."
PDRN Therapy uses polydeoxyribonucleotide, a regenerative compound derived from purified DNA fragments, to support tissue repair, reduce inflammation and improve overall skin quality. It has an established history in regenerative medicine before becoming popular in aesthetic treatments.
PDRN has a long-established safety record in wound healing and regenerative medicine, and is generally considered safe when administered by a trained professional, though a thorough consultation helps rule out any specific sensitivities.
PDRN Therapy in Chennai typically starts from ₹5,500 per session at Anucare. The final cost depends on the treatment area and number of sessions recommended for your specific skin goals.
PDRN works through a specific receptor-binding pathway that reduces inflammation and supports tissue repair, while PRP relies on growth factors released from your own blood platelets. PDRN does not require a blood draw, unlike PRP.
A course of 3 to 4 sessions, spaced 1 to 2 weeks apart, is generally recommended for visible, cumulative improvement in skin quality and resilience.
Topical numbing cream is applied before treatment, so most clients experience only mild discomfort during the micro-injections used in this treatment.
Downtime is minimal – most clients experience mild redness for about a day, which settles on its own. Normal activities can typically be resumed the same day.
Yes, PDRN Therapy is often combined with Dermapen 4 or HydraFacial as part of a broader skin revitalisation plan. Your dermatologist will advise on the right sequencing based on your specific goals.
Every PDRN Therapy session at our Anna Nagar clinic is performed only after a detailed skin assessment by experienced dermatologists, with treatment plan and injection technique customised to your skin’s specific needs.
Stay well hydrated before your appointment, and inform your dermatologist of any known allergies or sensitivities so suitability can be properly assessed.
Priya S