Melasma and deep pigmentation can be frustratingly resistant to regular skincare and even some in-clinic treatments, often because they involve overactive pigment-producing cells rather than just surface discolouration. Cosmelan Peel is a clinical-strength depigmentation protocol that works at the source of melanin production, combined with a structured home-care phase for comprehensive, lasting pigment correction.
At our Anna Nagar clinic, every Cosmelan Peel Treatment is performed only after a detailed skin assessment by experienced dermatologists to confirm the pigmentation type and design a home-care protocol suited to your skin’s tolerance and severity of pigmentation.
Cosmelan Peel is a two-phase depigmentation treatment developed to address melasma and stubborn pigmentation at a biological level rather than only exfoliating surface discolouration. In Phase 1, a clinical-strength mask is applied in-clinic, formulated with active ingredients that inhibit tyrosinase – the enzyme melanocytes rely on to produce melanin. By interrupting this pigment-production pathway, Cosmelan reduces the formation of new pigment rather than simply removing existing pigmented cells.
Phase 2 involves a structured home-care regimen using lower-strength maintenance creams over several weeks, designed to continue regulating melanin production while the skin’s surface gradually renews. This combination of in-clinic and at-home treatment is what differentiates Cosmelan from a standard Chemical Peel, which primarily works through surface exfoliation rather than addressing the underlying melanin-production pathway.
Because melasma is often triggered or worsened by hormonal factors, sun exposure and heat, Cosmelan is typically paired with strict, ongoing sun protection – without this, even a well-executed peel can see pigmentation gradually return, since UV exposure directly stimulates melanocyte activity. This is why Cosmelan is presented as a structured programme rather than a single one-time procedure.
At our Anna Nagar clinic, every Cosmelan Peel Treatment is performed only after a detailed skin assessment by experienced dermatologists to confirm the type and depth of pigmentation before designing a home-care protocol suited to your skin’s tolerance.
How Cosmelan Peel Helps:
Two-Phase Clinical Depigmentation Protocol
In-Clinic + 5-7 Day Home-Care
Most Skin Tones
1-2 Peel Cycles
5-7 Days Peeling
Required
₹5,400 Per Pack
Consultation & Pigmentation Assessment – our dermatologist evaluates pigmentation type and depth
Skin Preparation – cleansing and priming before mask application
Cosmelan Mask Application – clinical-strength mask applied and left on as advised
Mask Removal & Initial Guidance – mask removed and initial skin response reviewed
Home-Care Phase – structured maintenance creams used over 5-7 days and beyond
Follow-Up Review – progress checked and home-care adjusted as needed
Visible peeling begins within a few days
New, more even-toned skin emerges beneath
Continued fading with home-care maintenance
Sustained pigment control with consistent sun protection
Final cost depends on pigmentation severity and whether additional home-care kits are required.
Cosmelan is a well-established protocol when guided by trained professionals.
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Cosmelan Peel is a two-phase clinical depigmentation treatment that inhibits melanin production at the source using a tyrosinase-blocking mask, followed by a structured home-care regimen. It is primarily used to treat stubborn melasma and deep pigmentation.
Cosmelan is widely used for melasma and works differently from standard peels by targeting the melanin-production pathway itself, not just surface pigment. However, melasma can be stubborn and may require repeated cycles alongside consistent sun protection to maintain results.
Cosmelan Peel treatment in Chennai typically starts from ₹5,400 per pack at Anucare. The final cost depends on pigmentation severity and whether additional home-care kits are needed to complete the full protocol.
Cosmelan works by inhibiting the tyrosinase enzyme to reduce new melanin production, combined with a structured home-care phase, while a standard Chemical Peel primarily exfoliates existing pigmented surface cells without addressing the underlying production pathway in the same way.
Visible peeling typically begins within a few days of the in-clinic mask application, with noticeably more even-toned skin emerging over the following one to two weeks as the home-care phase continues.
The mask application itself is generally not painful, though some warmth or tingling may be felt. The peeling phase afterward can cause temporary tightness or sensitivity, similar to a mild sunburn.
Cosmelan is generally suitable for most skin tones, though a thorough consultation is essential since melanin-rich skin can be more prone to irritation-triggered pigmentation if aftercare and sun protection are not followed carefully.
Yes, visible peeling and redness for 5 to 7 days is an expected part of the Cosmelan process, unlike some gentler pigmentation treatments. Planning around this downtime, especially avoiding events during this window, is advised.
Yes, Cosmelan is often combined with Pico Laser for more comprehensive pigmentation correction, particularly for cases with both diffuse melasma and localised pigment spots. Your dermatologist will advise on the right sequencing.
Every Cosmelan Peel Treatment at our Anna Nagar clinic is performed only after a detailed skin assessment by experienced dermatologists, with the home-care protocol tailored to your pigmentation severity and skin tolerance.
Avoid retinoids, exfoliating acids and sun exposure for at least a week before your appointment, and be prepared to commit fully to the strict sun protection and home-care schedule that follows treatment.
Priya S